Home Health News Drug extends life of younger women with advanced breast cancer, study says – CNN

Drug extends life of younger women with advanced breast cancer, study says – CNN

6 min read
4
14

The study was conducted among 672 women under the age of 59 who received a drug called ribociclib, in combination with a common form of hormone therapy.
Seventy percent of the women who took the combination therapy were alive after 42 months according to the findings, compared to 46% for women who were treated with only the hormone therapy and a placebo.
This, the researchers said, corresponded to a 29% lower risk of death in patients receiving the combination therapy.
The results were presented at the annual meeting of the American Society of Clinical Oncology in Chicago Saturday and will be published Tuesday in the New England Journal of Medicine.
The study is the first to show a significant benefit in survival for premenopausal women with metastatic hormone-receptor positive breast cancer, according to lead author Dr. Sara Hurvitz, who directs the Breast Cancer Clinical Research Program at the UCLA Jonsson Comprehensive Cancer Center.
New tool calculates breast cancer risk with greater precisionNew tool calculates breast cancer risk with greater precision
“This trial was unique because it looks at younger women who haven’t gone through menopause,” said Hurvitz in a statement “This is an important group to study since advanced breast cancer is the leading cause of cancer death in women 20 to 59, and the vast majority of breast cancer is hormone-receptor positive.”
Women who received the ribociclib lived a median of 23.8 months without their disease progressing compared with 13 months for women who received the placebo.
“It’s great to see that we’re extending the length of someone’s life, not just the length of time their disease is controlled,” Hurvitz said. “Very few trials show an improvement in overall survival. That’s what is so phenomenal about the data.”
“Advanced breast cancer in pre-menopausal women can be very aggressive” said Dr. Harold Burstein of the Dana-Farber Cancer Institute in a statement. “It is important and encouraging to see a targeted therapy that significantly increases survival for younger women with this disease.” Burstein was not involved in the research.
Body fat levels linked to breast cancer risk in post-menopausal womenBody fat levels linked to breast cancer risk in post-menopausal women
Globally, breast cancer causes the greatest number of cancer-related deaths among women, according to the World Health Organization.
This year alone, it is estimated that 627,000 women died from breast cancer worldwide, which is about 15% of all cancer deaths among women, according to the WHO. In the United States, breast cancer is the most common cancer in women. About 41,000 women and 450 men die each year from breast cancer, according to the US Centers for Disease Control and Prevention.
Ribociclib and hormone therapy have been used to treat postmenopausal women with breast cancer previously and last year the combination therapy was approved by the US Food and Drug Administration for use in premenopausal women.
“This study confirms the benefits of these drugs are similar in both pre- and post-menopausal patients with advanced hormone receptor-positive breast cancers, and it further validates the clinical value of adding ribociclib for these patients,” said study co-author Dr. Debu Tripathy from the University of Texas MD Anderson Cancer Center.
The most common adverse reaction to the drug was a lowered white blood cell count, which can lead to infections.
The study was funded by pharmaceutical manufacturer Novartis which markets ribociclib under the brand name Kisqali. The drug, which is taken in pill form, costs over $12,000 a month, according to the prescription pricing website GoodRx.

Let’s block ads! (Why?)


Source link

4 Comments

  1. effient coupon

    September 9, 2019 at 1:21 pm

    Take enough time to prepare. As I apply more and more of these tips, I understand how your education has made you into a top expert in this field. How many people do you really think could possibly believe in this sortof stuff? You’re an outstanding story teller.

    Reply

  2. discountdrugnetwork.com

    September 15, 2019 at 6:54 am

    I’m not an expert but it looks to me like this data would be really useful if it were in the hands of the experts who knew how to apply it. I am naming my daughter after you. Moms andtiny cute animals probably like you. Ireally enjoyed every single minute of it.

    Reply

  3. shop now

    September 22, 2019 at 11:39 am

    Well I will never be the same person after reading this info! I truly appreciate individuals that do what you are doing! Many use websites to raise awareness. My biggest threat does not come from new competition. I really do like these points you’ve made here but I kind of doubt many can be used in the real world. It is very informative and you are obviously very knowledgeable in this area.

    Reply

  4. ventolin coupon

    September 24, 2019 at 4:56 am

    I’m continually browsing online for tips that can help me. This page was loaded when I started my phone. Hit me up if you’re able to. You are an awesome writer. Really sorry to bug you, but we could have just a couple more questions I’d like answers for. It’s very informative and I bet you are very knowledgeable in this area.

    Reply

Leave a Reply

Your email address will not be published. Required fields are marked *

Check Also

Cellphone-related head injuries became more common after the iPhone was released – The Verge

As cellphones got smarter, they also became marginally more dangerous to the clumsy, easil…