Home Health News Fecal transplant doctors offer rebuttal after patient's death – New York Post

Fecal transplant doctors offer rebuttal after patient's death – New York Post

4 min read


A procedure that was touted as the future of medicine left a patient dead last summer, and now doctors are bringing transparency to the still-new technology.

Doctors, books and blogs have been publicizing fecal microbiota transplantation (FMT) — a procedure where stool from a donor is transplanted into the intestinal tract of a recipient in order to restore healthy bacteria to the gut — for years as a possible cure-all for a spate of illnesses including ulcers, leukemia and liver disease.

But in June, the FDA announced that two people who had fecal transplants from the same donor got sick with E. coli — and one of them died. But few details were shared about the scary incidents.

Now, doctors at Massachusetts General Hospital, where the incidents took place, want to give their side of the story, and hopefully dispel some of the fear hanging over current clinical trials of the procedure.

They published their rebuttal Wednesday in the New England Journal of Medicine.

“We wanted to set the record straight,” co-author Dr. Elizabeth Hohmann, an associate professor of medicine and infectious diseases at Massachusetts General Hospital and Harvard Medical School, told NBC News.

Clinical trials are ongoing. The procedure was originally developed — and has been successfully used — to treat the superbug Clostridium difficile (C. diff), a life-threatening, diarrhea-producing, antibiotic-resistant infection.

In the report, the doctors explain that both cases used contaminated stool by the same donor, even though they were in different clinical trials — one for liver disease and the other for leukemia. After developing E. coli, even with extensive treatment, doctors weren’t able to save the patient with leukemia.

“This is a cautionary and sad tale,” Hohmann told NBC News. “It points out some of the important medical issues about immune-compromised [patients].”

The incidents were a lesson-learned situation, she continued.

“Maybe … changing the microbiome is not always a good idea,” she said of patients with compromised immune systems, such as those with cancer.

Even with the FDA’s new guidelines, which mandate both the poop and the donor be tested for “multidrug resistant organisms,” Hohmann warns that there are a lot of other organisms out there that aren’t being screened for.

“We can increase the ways we look for this,” she told NBC News. “But we can’t 100 percent eliminate it.”

Let’s block ads! (Why?)

Source link


  1. Lovie Mah

    June 4, 2021 at 2:07 pm

    This was awesome! I would like you to clean up all this spam though


  2. Patricia Vetsch

    June 13, 2021 at 12:29 am

    Have you ever heard of second life (sl for short). It is basically a online game where you can do anything you want. Second life is literally my second life (pun intended lol). If you would like to see more you can see these sl articles and blogs


  3. Stephane Sakamaki

    June 14, 2021 at 1:19 am

    I don’t know about you guys but I love airplanes. I had a friend in highschool that loves airplanes, so here are some airplane related stuff I don’t know about you guys but I love airplanes. I had a friend in highschool that loved airplanes, so here are some airplane related stuff https://www.airlinereporter.com/2010/05/video-airtran-making-special-livery-milwaukee-brewers/


  4. how to lose weight and keep it off

    September 24, 2021 at 3:36 am

    It’s hard to find expert men and women concerning this issue, but you seem like you understand what you’re speaking about! Many thanks


  5. NYC NY Local moving

    September 26, 2021 at 4:37 am

    Undoubtedly feel that which you said. Your preferred justification appeared to be over the internet the best matter to pay attention to. I say to you personally, I absolutely get irked though folks give thought to concerns that They only have no idea about. You managed to strike the nail on the best and described out The complete detail with out owning side-effects , people could have a sign. Will very likely be again to have extra. Thanks


Leave a Reply

Your email address will not be published. Required fields are marked *

Check Also

Did Nets’ Kevin Durant Undergo Crazy Body Transformation? (Photos) – Game 7 – Game7

[ad_1] Brooklyn Nets star Kevin Durant is already arguably the best player in the NBA. Alt…