WUHAN, China — As the worldwide number of COVID-19 cases reaches five million, the search for a vaccine has taken an important step forward. Researchers say the first human trial of a possible vaccine has been found to be safe and may effectively fight the virus.
Scientists in China say 108 healthy adults were given a dose of adenovirus type 5 vectored COVID-19 (Ad5-nCoV) during the trial. The drug uses a weakened strain of the common cold (adenovirus) to deliver genetic material which codes itself to find the protein in SARS-CoV-2 — the virus that causes COVID-19. These coded cells then head to the lymph nodes where the immune system creates antibodies that can recognize the virus and attack it.
“These results represent an important milestone. The trial demonstrates that a single dose of the new adenovirus type 5 vectored COVID-19 (Ad5-nCoV) vaccine produces virus-specific antibodies and T cells in 14 days,” Professor Wei Chen of the Beijing Institute of Biotechnology said in a statement.
Although Ad5 was found to create a rapid immune response in the body, scientists warn there’s no guarantee the drug will effectively fight the coronavirus.
“These results should be interpreted cautiously… The ability to trigger these immune responses does not necessarily indicate that the vaccine will protect humans from COVID-19. This result shows a promising vision for the development of COVID-19 vaccines, but we are still a long way from this vaccine being available to all,” Chen explained.
The test group of 18-60 year-olds was split into three groups of 36 and given either a small, medium, or large dose of Ad5. Researchers found that none of the patients suffered from serious reactions to the vaccine after four weeks. The most common side-effects included mild pain in the injection area, fever, and fatigue. The symptoms typically lasted for less than two days.
Rapid Response
The study, published in The Lancet, found that nearly every patient had more binding antibodies after 28 days. The antibodies, which learned to attach to the coronavirus, had increased by four times in 97 percent of the test group. Among the patients given the large dose of Ad5, 75 percent were found to have antibodies that can neutralize SARS-CoV-2 in their systems.
Patients also saw their T cell response increase rapidly, with nearly 93 percent seeing a rise in the body’s ability to fight off infections.
Vaccine Roadblocks
Researchers cautioned that Ad5 still has some issues. The biggest problem is that humans could be immune to adenovirus type 5. About half of the trial patients were found to have a pre-existing immunity to the cold virus which may have slowed the progress of the vaccine.
“Our study found that pre-existing Ad5 immunity could slow down the rapid immune responses to SARS-CoV-2 and also lower the peaking level of the responses,” said Professor Feng-Cai Zhu from Jiangsu Provincial Center for Disease Control and Prevention.
The final results of the Ad5 injections will be evaluated after six months. Researchers are hoping the patients will show a continued resistance to the coronavirus.
A second trial involving 500 healthy adults is already underway in Wuhan, the alleged starting point of the worldwide pandemic. This trial will also see how the drug affects patients over the age of 60.
Like studies? Follow us on Facebook!
Source link
and g
June 21, 2020 at 10:35 am
This design is wicked! You obviously know how to keep a reader entertained.
Between your wit and your videos, I was almost moved to start my own blog (well, almost…HaHa!) Wonderful job.
I really loved what you had to say, and more than that, how you presented it.
Too cool!
cbd oil that works 2020
June 27, 2020 at 11:08 am
Thanks for one’s marvelous posting! I seriously enjoyed reading it, you may be a
great author.I will be sure to bookmark your blog and will come back
from now on. I want to encourage yourself to continue your
great job, have a nice holiday weekend!
CPA near me
July 3, 2020 at 10:04 pm
I’m amazed, I must say. Seldom do I encounter a blog that’s both educative and amusing, and without a doubt, you have hit the nail on the head. The issue is something too few men and women are speaking intelligently about. Now i’m very happy I stumbled across this in my search for something regarding this.
Online Viagra
July 5, 2020 at 5:19 pm
Leading Online Pharmacy – Contact us at +1 (917) 259-3352 for unbelievable rates, discount and offers on any medicine. Get it delivered free of cost at your door steps, call us today. Phone : +1 (917) 259-3352
Investments
July 8, 2020 at 10:48 pm
An intriguing discussion is worth comment. I do think that you should publish more about this subject, it may not be a taboo subject but usually people do not speak about these issues. To the next! Best wishes!!
Digital Marketing Services
July 10, 2020 at 1:01 am
Leading Digital Marketing agency in India and Kolkata, Leading Web Design company. Providing web designing and Digital marketing services, Digital marketing course, and certification with an internship.
HolidayWeather
July 11, 2020 at 12:00 am
Hello there! I could have sworn I’ve visited this site before but after looking at many of the posts I realized it’s new to me. Regardless, I’m certainly delighted I stumbled upon it and I’ll be bookmarking it and checking back often!
binary options
July 11, 2020 at 5:11 pm
I like looking through an article that will make men and women think. Also, many thanks for allowing for me to comment!
Blogs for SEO
July 12, 2020 at 7:00 am
I must thank you for the efforts you’ve put in penning this site. I really hope to view the same high-grade content from you later on as well. In fact, your creative writing abilities has encouraged me to get my own blog now 😉
indian visa
July 13, 2020 at 12:11 am
Excellent article. I am experiencing some of these issues as well..
субсидиарная ответственность
July 14, 2020 at 3:04 am
Приходит время и директор компании приходит к решению о надвигающихся проблемах, которые не возможно будет преодолеть то в первую очередь его интересует непосредственно ликвидация ООО
cbd wholesale
July 15, 2020 at 3:09 am
I am the business owner of JustCBD label (justcbdstore.com) and I’m presently seeking to grow my wholesale side of business. I am hoping someone at targetdomain give me some advice ! I thought that the very best way to do this would be to reach out to vape shops and cbd retailers. I was hoping if anybody could recommend a trusted web site where I can purchase CBD Shops B2B Sales Leads I am currently looking at creativebeartech.com, theeliquidboutique.co.uk and wowitloveithaveit.com. Not sure which one would be the very best solution and would appreciate any guidance on this. Or would it be simpler for me to scrape my own leads? Suggestions?
nail doherty
July 15, 2020 at 8:35 pm
You are so cool! I don’t believe I have read through a single thing like this before. So great to discover somebody with a few unique thoughts on this subject. Seriously.. thanks for starting this up. This site is something that is required on the internet, someone with a bit of originality!
Website Marketing
July 16, 2020 at 2:49 pm
Hello there! I just want to offer you a huge thumbs up for your great info you have right here on this post. I will be coming back to your website for more soon.
UX Design Agency
July 17, 2020 at 3:47 am
The next time I read a blog, Hopefully it doesn’t disappoint me just as much as this one. I mean, Yes, it was my choice to read, however I really believed you would probably have something interesting to say. All I hear is a bunch of moaning about something that you could fix if you weren’t too busy searching for attention.
what not to do
July 17, 2020 at 11:02 am
Very good write-up. I certainly appreciate this site. Keep it up!
cbd tincture
July 18, 2020 at 7:39 am
I am the proprietor of JustCBD label (justcbdstore.com) and I am currently seeking to grow my wholesale side of business. I am hoping anybody at targetdomain share some guidance 🙂 I thought that the very best way to do this would be to reach out to vape companies and cbd retailers. I was really hoping if anyone could suggest a dependable website where I can buy Vape Shop B2B Database with Email Addresses I am already reviewing creativebeartech.com, theeliquidboutique.co.uk and wowitloveithaveit.com. Unsure which one would be the most suitable choice and would appreciate any support on this. Or would it be much simpler for me to scrape my own leads? Ideas?
Digital Marketing
July 19, 2020 at 7:51 am
Having read this I thought it was really informative. I appreciate you finding the time and effort to put this content together. I once again find myself personally spending way too much time both reading and posting comments. But so what, it was still worthwhile!
Click
July 19, 2020 at 8:10 am
Good post. I learn something new and challenging on websites I stumbleupon on a daily basis. It will always be helpful to read content from other authors and use a little something from their sites.
go x scooters
July 20, 2020 at 5:49 am
Having read this I believed it was very informative. I appreciate you spending some time and energy to put this information together. I once again find myself personally spending way too much time both reading and leaving comments. But so what, it was still worth it!
Blogger Task
July 22, 2020 at 12:49 am
Hi, I do think this is an excellent website. I stumbledupon it 😉 I will return once again since i have bookmarked it. Money and freedom is the greatest way to change, may you be rich and continue to help other people.
website host
July 22, 2020 at 2:13 am
My brother suggested I might like this website.
He was totally right. This post truly made my day. You can not imagine simply how much time I had spent
for this info! Thanks!
Short Sales
July 28, 2020 at 9:06 am
It’s hard to find educated people about this topic, but you sound like you know what you’re talking about! Thanks
Scam Reviews
July 28, 2020 at 7:10 pm
I’m amazed, I have to admit. Seldom do I encounter a blog that’s both educative and engaging, and let me tell you, you’ve hit the nail on the head. The issue is something which not enough people are speaking intelligently about. I am very happy that I stumbled across this during my hunt for something concerning this.
Keder Band
July 30, 2020 at 5:50 am
I really love your blog.. Great colors & theme. Did you build this amazing site yourself? Please reply back as I’m planning to create my very own site and would like to find out where you got this from or just what the theme is named. Appreciate it!
Lawn Care
July 30, 2020 at 8:56 am
You’ve made some good points there. I checked on the web for more information about the issue and found most people will go along with your views on this website.
Short Sales Experts
August 1, 2020 at 10:53 am
You’ve made some really good points there. I looked on the web to find out more about the issue and found most people will go along with your views on this website.
Best Techno Song
August 2, 2020 at 4:21 am
Wonderful article! We will be linking to this great article on our site. Keep up the great writing.
Scams Reviews
August 2, 2020 at 8:59 pm
Having read this I believed it was really informative. I appreciate you finding the time and energy to put this content together. I once again find myself spending a significant amount of time both reading and commenting. But so what, it was still worthwhile!
web hosting sites
August 14, 2020 at 8:03 am
I’m not sure why but this weblog is loading incredibly slow for
me. Is anyone else having this problem or is it
a issue on my end? I’ll check back later on and see if the problem still
exists.
Aldo Muncie
August 16, 2020 at 6:54 pm
After exploring a few of the blog posts on your site, I seriously appreciate your way of writing a blog. I book-marked it to my bookmark site list and will be checking back in the near future. Please visit my website as well and tell me your opinion.
cheap flights
August 26, 2020 at 7:14 pm
Having read this I believed it was rather enlightening.
I appreciate you finding the time and energy to put this information together.
I once again find myself spending a lot of time both reading
and leaving comments. But so what, it was still
worthwhile!
Curt Nocito
September 16, 2020 at 6:21 am
Howdy, I believe your web site could be having internet browser compatibility issues. When I take a look at your website in Safari, it looks fine however, when opening in I.E., it’s got some overlapping issues. I merely wanted to give you a quick heads up! Aside from that, great site!
Online games
November 2, 2020 at 7:28 am
Right here is the perfect webpage for anyone who really wants to find out about this topic. You realize so much its almost hard to argue with you (not that I personally would want to…HaHa). You definitely put a new spin on a subject that has been discussed for decades. Excellent stuff, just wonderful!
Virseal
November 7, 2020 at 8:32 pm
Hello! I could have sworn I’ve visited this blog before but after looking at many of the posts I realized it’s new to me. Anyhow, I’m definitely happy I stumbled upon it and I’ll be book-marking it and checking back regularly!
Sanora Hamblen
February 1, 2021 at 9:26 pm
This is a very interesting article. Please, share more like this!
viagra canada
February 26, 2021 at 5:39 am
https://genericviagragog.com cheap viagra
Youtube Video Download
April 7, 2021 at 4:32 pm
Nice Article to download YouTube videos by using https://ytzip.com Open ytzip.com Youtube video download website and enter the video’s URL to the corresponding field, at the top of the page. Click “Download” and youtube video download will begin.