Home Health News iBio Provides Update on IBIO-201 COVID-19 Vaccine Program – GlobeNewswire

iBio Provides Update on IBIO-201 COVID-19 Vaccine Program – GlobeNewswire

10 min read

NEW YORK, Aug. 10, 2020 (GLOBE NEWSWIRE) — iBio, Inc. (NYSE AMERICAN:IBIO) (“iBio” or the “Company”), a biotechnology corporation and biologics contract manufacturing organization, today provided an update on one of its proprietary vaccine candidates being designed to prevent infection from the SARS-CoV-2 virus. iBio is investigating an array of adjuvants in combination with iBio’s proprietary lichenase carrier molecule (“LicKMTM”) fused to a coronavirus subunit protein (“IBIO-201”) with the goal of producing a safe and effective vaccine for COVID-19 disease, and especially one for our most vulnerable populations, including the elderly.

Ten distinct preclinical study arms for the IBIO-201 antigen-adjuvant combinations have been concluded.  These include combinations delivered via intramuscular and intranasal routes, and datasets are under evaluation.

Anti-SARS-CoV-2 spike titers to IBIO-201were observed 21 days after immunization.  Titers continued to increase over the 42-day study. Distinct, favorable Th1 and Th2 immune profiles were observed.

Early functional testing of mouse antisera from IBIO-201 immunized mice demonstrates the presence of antibodies that interfere with the binding of SARS-CoV-2 spike protein sequences to human ACE2 in ex vivo assays. iBio plans to conduct additional testing of IBIO-201 antisera, including further evaluations of neutralizing titers in multiple assay formats. In addition, significant immune profiling studies are ongoing to evaluate safety and immune protection correlates, including antigen-specific T cell responses and memory B cell testing. The additional testing for both IBIO-201 and IBIO-200 is occurring in collaboration with the Texas A&M University System (“TAMUS”) laboratories.

“We are encouraged by these pre-clinical data, which demonstrate IBIO-201’s ability to generate an immune response to SARS-CoV-2 sequences and neutralize protein interaction,” said Tom Isett, Chairman & CEO of iBio. “We expect to gain more insight as we complete data analysis of both of our COVID-19 vaccine candidates.”

About iBio’s COVID-19 Vaccine Development Programs

On March 11, 2020, the Company filed four provisional patent applications with the U.S. Patent and Trademark Office in support of its COVID-19 vaccine platforms. The virus-like particle (“VLP”) program (“IBIO-200”) was subsequently announced on March 18, 2020. The LicKM-Subunit program (“IBIO-201”) was announced on June 3, 2020. If the program(s) move into clinical trials, iBio has the capability to rapidly develop and manufacture at clinical and commercial scales in its 130,000 square foot facility in Bryan, Texas. Originally built in 2010 with funding from the U.S. Defense Advanced Research Projects Agency [DARPA], iBio’s FastPharming Facility® was part of the “Blue Angel” initiative to establish factories capable of rapid delivery of medical countermeasures in response to a disease pandemic.

About iBio, Inc.

iBio is a global leader in plant-based biologics manufacturing. Its FastPharming System® combines vertical farming, automated hydroponics, and glycan engineering technologies to rapidly deliver high-quality monoclonal antibodies, vaccines, bioinks and other proteins. The Company’s subsidiary, iBio CDMO LLC, provides FastPharming Contract Development and Manufacturing Services. iBio’s FastGlycaneering Development Service™ includes an array of new glycosylation technologies for engineering high-performance recombinant proteins. Additionally, iBio is developing proprietary products, which include IBIO-100 for the treatment of fibrotic diseases, and vaccines for COVID-19 disease. For more information, visit www.ibioinc.com.

Certain statements in this press release constitute “forward-looking statements” within the meaning of the federal securities laws. Words such as “may,” “might,” “will,” “should,” “believe,” “expect,” “anticipate,” “estimate,” “continue,” “predict,” “forecast,” “project,” “plan,” “intend” or similar expressions, or statements regarding intent, belief, or current expectations, are forward-looking statements. These forward-looking statements are based upon current estimates and assumptions and include statements regarding  producing a safe and effective vaccine for COVID-19 disease and  especially one for our most vulnerable populations, including the elderly, plans to conduct additional testing of IBIO-201 antisera, including further evaluations of neutralizing titers in multiple assay formats, and gaining more insight as we complete data analysis of both of our COVID-19 vaccine candidates. While the Company believes these forward-looking statements are reasonable, undue reliance should not be placed on any such forward-looking statements, which are based on information available to us on the date of this release. These forward-looking statements are subject to various risks and uncertainties, many of which are difficult to predict that could cause actual results to differ materially from current expectations and assumptions from those set forth or implied by any forward-looking statements. Important factors that could cause actual results to differ materially from current expectations include, among others, the Company’s ability to successfully complete additional testing planned for both SARS-CoV-2 vaccine candidates, IBIO-201 and IBIO-200, and to produce a safe and effective vaccine for COVID-19 disease, the Company’s ability to obtain regulatory approvals for commercialization of its product candidates, including its COVID-19 vaccines, or to comply with ongoing regulatory requirements, regulatory limitations relating to its ability to promote or commercialize its product candidates for specific indications, acceptance of its product candidates in the marketplace and the successful development, marketing or sale of products, its ability to maintain its license agreements, the continued maintenance and growth of its patent estate, its ability to establish and maintain collaborations, its ability to obtain or maintain the capital or grants necessary to fund its research and development activities, competition, or its ability to retain its key employees and the other factors discussed in the Company’s Annual Report on Form 10-K for the year ended June 30, 2019 and the Company’s subsequent filings with the SEC, including subsequent periodic reports on Forms 10-Q and 8-K. The information in this release is provided only as of the date of this release, and we undertake no obligation to update any forward-looking statements contained in this release on account of new information, future events, or otherwise, except as required by law.


Stephen Kilmer
iBio, Inc.
Investor Relations
(646) 274-3580

Let’s block ads! (Why?)

Source link


  1. Merlin Deloge

    August 11, 2020 at 5:38 am

  2. Nick Paguin

    October 23, 2020 at 7:57 pm

    This is especially essential in people that


  3. Celestine Alzaga

    October 29, 2020 at 10:16 am

    Your writing is the best.


  4. 출장안마

    October 29, 2020 at 4:49 pm

    good job


  5. Ambrose Clippinger

    November 4, 2020 at 1:32 pm

    good job.


  6. 출장안마

    November 5, 2020 at 1:31 am

    I love your blog. I’m experienced. Thank an individual.


  7. 출장마사지

    November 9, 2020 at 10:16 am

    Thank anyone so much for letting us know what We didn’t know. I count on working with you.


  8. 죠스출장

    November 14, 2020 at 7:19 am

    I was so pleased from your blog. Thank a person so much.


  9. 죠스출장안마

    November 15, 2020 at 9:14 am

    I love your website. I’m faced. Thank you.


  10. 죠스출장안마

    November 15, 2020 at 8:36 pm

    Wow, the articles are so sexy. How may I actually write like you? My spouse and i are looking for the similar writing skills as you may.


  11. 죠스출장마사지

    November 16, 2020 at 8:47 am

    Amazing. If you’re so good of which you’re so good at this time. Your help woke us up. Thank you really much.


  12. 테즈출장마사지

    November 16, 2020 at 9:59 am

    Regards to you, My spouse and i learned something new. Thank you so much. I glimpse forward to working with you.


  13. 테즈출장샵

    November 17, 2020 at 1:00 pm

    Exactly what a man of power! You have the ability to publish excellent items that you can’t come across anywhere. to envy


  14. 탑텐출장마사지

    November 19, 2020 at 12:13 pm

    I love your website. I’m faced. Thank an individual.


  15. 마사지구인구직

    November 20, 2020 at 6:33 am

    Thanks to you, I realized something new. Thank you so much. I seem forward to working with you.


  16. 출장안마

    November 20, 2020 at 10:59 pm

    Greetings! Very useful advice in this particular article! It’s the little changes that make the largest changes. Thanks a lot for sharing!


  17. 제주출장안마 후불

    November 24, 2020 at 5:13 pm

    This site was… how do I say it? Relevant!! Finally I have found something that helped me. Appreciate it!


  18. 출장안마

    November 26, 2020 at 12:20 pm

    Pretty! This was a really wonderful article. Many thanks for supplying this info.


  19. 구미출장안마

    December 4, 2020 at 3:29 pm

    Pretty! This was an incredibly wonderful post. Many thanks for providing this info.


  20. 대전 출장

    December 6, 2020 at 8:42 pm

    An outstanding share! I have just forwarded this onto a colleague who was doing a little research on this. And he actually bought me breakfast simply because I stumbled upon it for him… lol. So allow me to reword this…. Thanks for the meal!! But yeah, thanx for spending time to talk about this issue here on your web site.


  21. 일산요정

    December 7, 2020 at 12:59 am

    Pretty! This has been an incredibly wonderful article. Thanks for providing this info.


  22. 포항출장

    December 7, 2020 at 10:16 pm

    I used to be able to find good info from your blog articles.


  23. 출장마사지

    December 17, 2020 at 11:22 pm

    Hi, I do believe this is an excellent site. I stumbledupon it 😉 I am going to revisit yet again since i have book-marked it. Money and freedom is the greatest way to change, may you be rich and continue to help other people.


  24. 구찌출장마사지

    December 20, 2020 at 5:08 pm

    Spot on with this write-up, I seriously feel this website needs a lot more attention. Iíll probably be returning to read more, thanks for the information!


  25. 구찌출장안마

    December 21, 2020 at 4:10 am

    At this rate, you can debut as a copy writer. Now i am so touched. I am just cheerful to meet you. Say thanks to you.


  26. 구찌출장

    December 22, 2020 at 1:07 am

    Wow. Occur to be so good of which you’re so good at this time. Your help woke everyone up. Thank you really much.


  27. 용인출장마사지

    December 23, 2020 at 8:11 pm

    After looking into a few of the blog articles on your web page, I seriously appreciate your way of writing a blog. I added it to my bookmark webpage list and will be checking back in the near future. Take a look at my website too and tell me your opinion.


  28. 마사지구인구직

    December 30, 2020 at 6:22 am

    Good article. I am facing many of these issues as well..


  29. 마사지구인구직

    December 30, 2020 at 11:05 pm

    I blog often and I seriously appreciate your information. This article has really peaked my interest. I am going to bookmark your website and keep checking for new details about once a week. I opted in for your Feed too.


  30. 제주출장마사지

    January 3, 2021 at 4:14 am

    Good web site you have here.. Itís hard to find quality writing like yours these days. I really appreciate people like you! Take care!!


  31. 제주출장안마

    January 4, 2021 at 5:47 pm

    I truly love your blog.. Excellent colors & theme. Did you create this web site yourself? Please reply back as Iím looking to create my own personal blog and would like to know where you got this from or just what the theme is named. Appreciate it!


  32. 제주출장안마

    January 6, 2021 at 11:19 am

    This is a topic that is near to my heart… Best wishes! Exactly where are your contact details though?


  33. 제주 출장안마

    January 6, 2021 at 11:07 pm

    Excellent article. I definitely love this website. Thanks!


  34. 천안출장안마

    January 8, 2021 at 12:52 pm

    Aw, this was an incredibly nice post. Finding the time and actual effort to generate a top notch articleÖ but what can I sayÖ I put things off a lot and don’t manage to get nearly anything done.


  35. 전주출장마사지

    January 9, 2021 at 9:13 am

    You have made some really good points there. I checked on the net for more info about the issue and found most people will go along with your views on this site.


  36. 출장안마

    January 10, 2021 at 3:04 pm

    Hi, I think your web site could be having browser compatibility problems. When I look at your web site in Safari, it looks fine however, if opening in Internet Explorer, it has some overlapping issues. I merely wanted to provide you with a quick heads up! Other than that, excellent blog!


  37. 출장

    January 10, 2021 at 7:44 pm

    I really love your website.. Excellent colors & theme. Did you develop this amazing site yourself? Please reply back as I챠m wanting to create my own website and would like to know where you got this from or just what the theme is named. Thanks!


  38. 부천출장

    January 11, 2021 at 8:58 pm

    This web site certainly has all the information and facts I needed concerning this subject and didnít know who to ask.


  39. 출장마사지

    January 13, 2021 at 5:03 am

    Excellent article! We will be linking to this particularly great content on our website. Keep up the great writing.


Leave a Reply

Your email address will not be published. Required fields are marked *

Check Also

Los Angeles County, known for strict lockdowns, hits 1M COVID cases – New York Post

Los Angeles County this weekend surpassed 1 million COVID-19 cases since th…

Must Read

Load more