Home Health News U.K. Backs Cambridge Plan for Vaccine Against Many Coronaviruses – Bloomberg

U.K. Backs Cambridge Plan for Vaccine Against Many Coronaviruses – Bloomberg

3 min read
4
20

Scientists from the University of Cambridge won funding from the U.K. government to start trials for a DNA-based vaccine that aims to protect against multiple coronaviruses.

The government has invested 1.9 million pounds ($2.5 million) to develop the shot, with the researchers planning to begin phase I trials in the autumn, the university said in a statement Wednesday. The team aims to use genetic sequences of other known coronaviruses to create one vaccine that goes beyond Covid-19 to fight related diseases such as Middle East respiratory syndrome, or MERS.

More than 30 Covid vaccines are in clinical trials, with at least 140 more at the preclinical stage, according to the World Health Organization. Frontrunners include the University of Oxford, working with AstraZeneca Plc, and Moderna Inc.

The pandemic has spurred the development of a wave of new approaches to vaccine-making, with a race to see which modality will be the first and most successful. A handful of DNA-based vaccines are being tested, including one from Inovio Pharmaceuticals Inc. The company said an early trial showed positive immune responses, but investors complained about a lack of detail.

The Cambridge team’s shot uses computer-generated antigen structures that train the immune system to target key parts of the virus and produce the appropriate antiviral response. One benefit of this approach, according to Jonathan Heeney, a Cambridge professor who is leading the study, is that it should avoid any adverse hyper-inflammatory immune reactions.

“We’re looking for chinks in its armor, crucial pieces of the virus that we can use to construct the vaccine to direct the immune response in the right direction,” he said. “Ultimately we aim to make a vaccine that will not only protect from SARS-CoV-2, but also other related coronaviruses that may spill over from animals to humans.”

— With assistance by David Hellier

    Let’s block ads! (Why?)


    Source link

    4 Comments

    1. Yon Muscott

      November 12, 2020 at 2:03 pm

      I’d have to examine with you here. Which is not one thing I usually do! I take pleasure in reading a post that may make folks think. Additionally, thanks for permitting me to comment!

      Reply

    2. zortilonrel

      November 13, 2020 at 12:20 pm

      Great ?V I should definitely pronounce, impressed with your website. I had no trouble navigating through all tabs as well as related information ended up being truly easy to do to access. I recently found what I hoped for before you know it at all. Reasonably unusual. Is likely to appreciate it for those who add forums or anything, website theme . a tones way for your client to communicate. Excellent task..

      Reply

    3. Sanford Macina

      January 12, 2021 at 6:33 am

      I enjoyed reading your pleasant website. I see you offer priceless info. stumbled into this website by chance but I’m sure glad I clicked on that link. You definitely answered all the questions I’ve been dying to answer for some time now. Will definitely come back for more of this.

      Reply

    4. frolep rotrem

      February 6, 2021 at 6:27 pm

      I was more than happy to search out this net-site.I wished to thanks for your time for this glorious learn!! I definitely having fun with each little little bit of it and I have you bookmarked to take a look at new stuff you weblog post.

      Reply

    Leave a Reply

    Your email address will not be published. Required fields are marked *

    Check Also

    With obesity on the rise, the best diet may be tailored to our genes, experts say – ABC News

    With the COVID-19 pandemic drawing more attention to America’s obesity problem, a gr…