Home Health News J&J: most Phase 1/2a participants in COVID-19 vaccine developed neutralizing antibodies – MarketWatch

J&J: most Phase 1/2a participants in COVID-19 vaccine developed neutralizing antibodies – MarketWatch

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Shares of Johnson & Johnson
JNJ,
+0.89%

were up 0.1% in trading on Friday after data from the Phase 1/2a clinical trial for its COVID-19 vaccine candidate was published as a preprint. A preprint is not a peer-reviewed study, long considered the gold standard in medical research; however, some drugmakers developing vaccines and treatments are publishing clinical-trial findings on preprint servers during the coronavirus pandemic. The study evaluated a one-dose and two-dose regimen in two cohorts of participants: healthy adults between the ages of 18 and 55 years old and those between the ages of 65 and 75 years old. Interim results reported by J&J in the preprint indicate that 99% of the adult participants who received the vaccine developed neutralizing antibody titers, and all of the 65-and-older participants did, as well. Both groups had binding and neutralizing antibody levels that were in “the same range” as people who have recovered from COVID-19 infections. “Based on similar immunogenicity of both dose levels, we have selected the lower dose for further clinical evaluation,” the researchers said. Earlier this week J&J had announced that it had initiated a Phase 3 trial in the U.S. utilizing a single dose. J&J’s stock is 0.7% so far this year, while the S&P 500
SPX,
+1.77%

is up 0.5%.

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3 Comments

  1. Loraine Datcher

    May 11, 2021 at 11:57 am

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  2. Rodger Caple

    June 6, 2021 at 5:48 pm

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    Reply

  3. Ana Studdiford

    June 10, 2021 at 11:32 am

    This was awesome! I would like you to clean up all this spam though

    Reply

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