Home Health News What Should Investors Know About 2-Dose COVID Vaccines? – The Motley Fool

What Should Investors Know About 2-Dose COVID Vaccines? – The Motley Fool

8 min read
41
9

There is a small amount of data that suggests only one dose of a coronavirus vaccine in a two-dose schedule can provide some protection against the coronavirus. Does this mean that people could safely receive one dose instead of two? Is it too late for investors to start paying attention to companies working on a single-dose vaccine, like Johnson & Johnson (NYSE:JNJ)? Dr. Bruce Gellin of the Sabin Vaccine Institute joined Olivia Zitkus and Corinne Cardina of Fool.com’s Healthcare and Cannabis Bureau on a Dec. 18 episode of Fool Live to discuss the two-dose vaccines from Moderna (NASDAQ:MRNA) and Pfizer (NYSE:PFE)BioNTech (NASDAQ:BNTX) team.

[embedded content]

Olivia Zitkus: Both of these vaccines are mRNA vaccines, messenger RNA vaccines. While the two mRNA vaccines are intended to be a two-dose regimen, you vaccinate a person and then they return three or four weeks later depending on the vaccine for their second dose, some people are wondering about the potential for just one dose of these mRNA vaccines. Notably an opinion article in the New York Times published just today, I believe this morning, questioned the possibility of getting more people vaccinated by administering just one of the two intended doses. I’m wondering what your thoughts are on this, and what is the impact of these kinds of conversations on the public’s behavior?

Dr. Bruce Gellin: It’s an important question. I think that part of this is recognizing, I mean there are 300 different approaches that are being taken globally and you probably tracking every one of those, but I think what’s interesting is that there’s so much interest, so much attention. Any scientist who has an approach to vaccine has come forward, and we’re going to learn a lot from that. Not all 300 horses are going to end the race, but I think we’re going to learn a lot in that process. But as far as this one and two dose, there are a couple of companies that are focusing on a single dose. I think that’s really important when you think about usability. For a program standpoint, finding a person for the first time to get vaccinated is hard enough, getting them to come back when they need to is really a much more complicated challenge which we’re going to have to deal with to try to make sure we provide protection. But the question that’s really important, what was intriguing, and I think that’s probably the best you can say from the data was that both of these mRNA vaccines are two-dose vaccines. The initial clinical trials of phase 1 and phase 2 trials are designed to determine what’s the right dose, what’s the right dose interval, and it shows that the maximum immune response is after two doses. But because they were looking intensively in these studies, you could follow-up people after that first dose, and you saw that about the two-week mark, 10 days, 14 days, there was a splitting in the curve. What that means is that at about 14 days, some people even after first dose seem to be protected when compared to the placebo. Interesting, encouraging, but very small numbers. While we’ve seen these what’s called a point estimate, when you compare those numbers, it is in the 50-ish percentages, that’s intriguing but since there’s such small numbers, a confidence limit, as statisticians say is quite wide, and if there was one or two differences in those who is in the placebo group or not, it will be quite different. The short story is until we know a lot more, two doses is what we need, and giving them a first dose could actually cause a difficulty if people don’t get the full immunity they need. In doing so, we’ll be using a lot of vaccines that might not be protecting the population as we think.

Zitkus: Right, that length of the immunity is still a question with the two-dose vaccine. If we have people just getting one dose of a two dose schedule then that really complicates the data picture.

Gellin: In fact, so looking at the immunology of coronaviruses and other vaccines, we don’t expect lifelong protection but maybe we’ll be surprised. Given what we know about vaccinology and immune response, a second dose is likely to give a better and longer response.

Let’s block ads! (Why?)


Source link

41 Comments

  1. akfSDnJmCej

    January 13, 2021 at 12:39 pm

    616277 528110extremely nice post, i really adore this web website, carry on it 305567

    Reply

  2. Homepage

    January 13, 2021 at 2:20 pm

    … [Trackback]

    […] Informations on that Topic: blog.sleepingrex.com/2020/12/26/what-should-investors-know-about-2-dose-covid-vaccines-the-motley-fool/ […]

    Reply

  3. frolep rotrem

    February 6, 2021 at 9:14 pm

    Hiya, I am really glad I have found this info. Nowadays bloggers publish only about gossips and web and this is really annoying. A good web site with interesting content, that is what I need. Thank you for keeping this website, I will be visiting it. Do you do newsletters? Can not find it.

    Reply

  4. elangqq

    February 14, 2021 at 3:56 pm

    201911 951375Just a smiling visitor here to share the love (:, btw outstanding style . “Audacity, far more audacity and always audacity.” by Georges Jacques Danton. 959012

    Reply

  5. fifaqq

    February 15, 2021 at 5:18 pm

    Excellent article. Keep posting such kind of info on your
    page. Im really impressed by your blog.
    Hey there, You’ve performed a fantastic job. I’ll definitely digg it and personally recommend to my friends.

    I am confident they’ll be benefited from this site.

    Reply

  6. www.2qiuqiu99.club

    February 16, 2021 at 1:47 am

    371448 837973You got a really great website, Gladiola I discovered it via yahoo. 64227

    Reply

  7. Houston Electricity Rates

    February 26, 2021 at 11:15 pm

    770830 259325 There is noticeably a bundle to know about this. I assume you made certain good points in attributes also. 368282

    Reply

  8. بت فوروارد فارسی

    March 2, 2021 at 7:04 pm

    835810 253178This web site is really a walk-through it genuinely could be the details you wanted concerning this and didnt know who to inquire about. Glimpse here, and you will absolutely discover it. 973257

    Reply

  9. buy kimber rifles online

    March 9, 2021 at 2:37 pm

    206709 77939Outstanding post, I conceive individuals really should larn a whole lot from this weblog its quite user friendly . 173321

    Reply

  10. Beställ OxyContin i Sverige

    March 14, 2021 at 5:14 pm

    942886 239086This really is an superb write-up and I completely recognize exactly where your coming from in the third section. Perfect read, Ill regularly follow the other reads. 782898

    Reply

  11. boiling crab

    March 15, 2021 at 5:19 pm

    974858 122782Really good post. I just stumbled upon your weblog and wanted to say that Ive truly enjoyed surfing about your blog posts. After all I is going to be subscribing to your feed and I hope you write once again quite soon! 289496

    Reply

  12. 345661 941197youve gotten an essential weblog proper here! would you wish to make some invite posts on my weblog? 321567

    Reply

  13. relx pod

    March 21, 2021 at 11:32 pm

    829916 370195Hey there! Good stuff, please keep us posted when you post once more something like that! 31869

    Reply

  14. PPO

    March 23, 2021 at 11:18 pm

    77673 313906I cannot thank you fully for the blogposts on your internet page. I know you placed a lot of time and effort into all of them and hope you know how considerably I appreciate it. I hope I will do precisely exactly the same for yet another individual at some point. Palm Beach Condos 822267

    Reply

  15. little nightmares 2

    March 24, 2021 at 11:35 pm

    447195 992850I adore your wordpress web template, wherever would you download it from? 978319

    Reply

  16. Sexual orientation of transwomen

    March 30, 2021 at 10:55 am

    291486 270464When do you think this Real Estate market will go back in a positive direction? Or is it still too early to tell? We are seeing plenty of housing foreclosures in Altamonte Springs Florida. What about you? Would love to get your feedback on this. 641070

    Reply

  17. replica tag heuer band

    April 1, 2021 at 11:15 am

    685433 872448I conceive this internet site contains some rattling superb data for every person : D. 52398

    Reply

  18. Glo Carts

    April 12, 2021 at 11:41 am

    741731 896427I really happy to uncover this website on bing, just what I was looking for : D too bookmarked . 759563

    Reply

  19. 888609 353493The planet are in fact secret by having temperate garden which are generally beautiful, rrncluding a jungle that is definitely undoubtedly profligate featuring so numerous systems by way of example the game courses, golf method and in addition private pools. Hotel reviews 119824

    Reply

  20. Predrag Timotić

    April 21, 2021 at 3:47 am

    10850 382185Just wanna remark on few general items, The internet site style is perfect, the subject matter is rattling excellent 938867

    Reply

  21. buy morphine online

    April 25, 2021 at 2:53 am

    219347 105592After examine a couple of with the weblog posts on your website now, and I truly like your way of blogging. I bookmarked it to my bookmark website list and shall be checking again soon. Pls try my web site online as effectively and let me know what you believe. 169477

    Reply

  22. Dallas Electricity Rates

    April 26, 2021 at 10:14 pm

    389858 314934Id always want to be update on new content on this website , saved to fav! . 118409

    Reply

  23. World Market URL

    April 27, 2021 at 10:57 pm

    296764 559878Spot on with this write-up, I really suppose this website needs considerably more consideration. probably be once more to learn way more, thanks for that information. 419011

    Reply

  24. 대밤

    April 28, 2021 at 9:21 am

    627497 210330Spot on with this write-up, I should say i believe this superb site needs much a lot more consideration. Ill probably be once once again to learn an excellent deal far more, numerous thanks that info. 873178

    Reply

  25. Car Parking

    April 29, 2021 at 10:12 pm

    657388 351157This write-up contains great original thinking. The informational content here proves that issues arent so black and white. I feel smarter from just reading this. 390810

    Reply

  26. https://wazobet.com/

    April 30, 2021 at 10:38 pm

    641826 913349Cheapest speeches and toasts, as nicely as toasts. probably are designed building your personal at the party and is going to be most likely to turn into witty, humorous so new even. very best man toast 419374

    Reply

  27. ดูบอลสด

    May 1, 2021 at 11:12 pm

    539946 182125Nicely worded post will likely be sharing this with my readers this evening 602705

    Reply

  28. White House Market Darknet

    May 2, 2021 at 11:43 am

    474908 248127Good site. On your blogs quite interest and i will tell a buddies. 886556

    Reply

  29. ดูบอล

    May 4, 2021 at 10:45 pm

    736383 520204Dude.. My group is not considerably into seeking at, but somehow I acquired to read several articles on your blog. Its amazing how interesting its for me to check out you fairly often. 857549

    Reply

  30. ดูบอลออนไลน์

    May 5, 2021 at 10:34 pm

    217256 719798Some truly quality blog posts on this web site , saved to my bookmarks . 149453

    Reply

  31. relxbycake.com

    May 6, 2021 at 10:22 pm

    85486 937288You produced some very first rate factors there. I regarded on the web for the dilemma and located many people will associate with with your site. 185191

    Reply

  32. ดูบอล

    May 6, 2021 at 11:22 pm

    733513 113768This web site is my breathing in, real amazing style and perfect content material . 721870

    Reply

  33. ดูบอลสด

    May 8, 2021 at 12:04 am

    356501 678892Enjoyed reading this, very excellent stuff, thankyou . 635878

    Reply

  34. ดูบอลสด

    May 8, 2021 at 10:36 pm

    504491 297829You produced some decent points there. I looked on-line for any difficulty and identified most individuals will go in conjunction with along with your site. 645417

    Reply

  35. ดูบอล

    May 9, 2021 at 10:26 pm

    958310 455322you make running a blog glance 384637

    Reply

  36. Kim Ybanez

    May 10, 2021 at 7:44 am

    Have you ever heard of second life (sl for short). It is essentially a game where you can do anything you want. SL is literally my second life (pun intended lol). If you would like to see more you can see these Second Life articles and blogs

    Reply

  37. 997226 522901Hey, you?re the goto expert. Thanks for haingng out here. 21479

    Reply

  38. Beretta Shotgun Stocks For Sale

    May 12, 2021 at 7:25 am

    934885 83055Amazing weblog layout here. Was it hard creating a nice searching internet site like this? 448854

    Reply

  39. pialapoker

    May 13, 2021 at 10:25 pm

    455024 305914Cheers for this exceptional. I was wondering whether you were preparing of publishing similar posts to this. .Maintain up the excellent articles! 295874

    Reply

  40. jekpot88

    May 13, 2021 at 10:26 pm

    32897 491380The next time I learn a weblog, I hope that it doesnt disappoint me as much as this one. I mean, I do know it was my choice to read, even so I truly thought youd have something attention-grabbing to say. All I hear is really a bunch of whining about something which you could fix for those that werent too busy in search of attention. 417982

    Reply

  41. coupons for everything

    May 14, 2021 at 2:25 am

    995940 705255if the buffalo in my head could speak german i would not know a god damm thing. What i do know is that the language of art is out of this world. 369859

    Reply

Leave a Reply

Your email address will not be published. Required fields are marked *

Check Also

British Nutrition Foundation to launch Healthy Eating Week – New Food

The BNF is launching a new event to encourage people from all ages to improve their health…