Home Health News Pfizer/BioNTech vaccine appears effective against mutation in new coronavirus variants -study – Reuters

Pfizer/BioNTech vaccine appears effective against mutation in new coronavirus variants -study – Reuters

4 min read

NEW YORK (Reuters) – Pfizer Inc and BioNTech’s COVID-19 vaccine appeared to work against a key mutation in the highly transmissible new variants of the coronavirus discovered in the UK and South Africa, according to a laboratory study conducted by the U.S. drugmaker.

A healthcare worker prepares a Pfizer coronavirus disease (COVID-19) vaccination in Los Angeles, California, U.S., January 7, 2021. REUTERS/Lucy Nicholson

The not-yet peer reviewed study by Pfizer and scientists from the University of Texas Medical Branch indicated the vaccine was effective in neutralizing virus with the so-called N501Y mutation of the spike protein.

The mutation could be responsible for greater transmissibility and there had been concern it could also make the virus escape antibody neutralization elicited by the vaccine, said Phil Dormitzer, one of Pfizer’s top viral vaccine scientists.

The study was conducted on blood taken from people who had been given the vaccine. Its findings are limited, because it does not look at the full set of mutations found in either of the new variants of the rapidly spreading virus.

Dormitzer said it was encouraging that the vaccine appears effective against the mutation, as well as 15 other mutations the company has previously tested against.

“So we’ve now tested 16 different mutations, and none of them have really had any significant impact. That’s the good news,” he said. “That doesn’t mean that the 17th won’t.”

Dormitzer noted another mutation found in the South African variant, called the E484K mutation, is also concerning.

The researchers plan to run similar tests to see if the vaccine is effective against other mutations found in the UK and South African variants and hope to have more data within weeks.

Scientists have expressed concern that vaccines being rolled out may not be able to protect against the new variants, particularly the one that emerged in South Africa.

Simon Clarke, an associate professor in cellular microbiology at the University of Reading, said this week that while both variants had some new features in common, the one found in South Africa “has a number additional mutations” that included more extensive alterations to the spike protein.

The Pfizer/BioNTech vaccine and the one from Moderna Inc, which use synthetic messenger RNA technology, can be quickly tweaked to address new mutations of a virus if necessary. Scientists have suggested the changes could be made in as little as six weeks.

Reporting by Michael Erman; Editing by Bill Berkrot and Edwina Gibbs

Let’s block ads! (Why?)

Source link


  1. Neil Hammette

    January 12, 2021 at 3:30 am

    some tanning salons have high power uv lamps which can shorten the amount of time you need to expose yourself::


  2. design

    April 14, 2021 at 4:25 pm

    Good way of explaining, and nice post to obtain information about my presentation topic, which i am going
    to present in college.


  3. Emil Capellas

    May 11, 2021 at 2:23 pm

    Have you ever heard of second life (sl for short). It is basically a video game where you can do anything you want. sl is literally my second life (pun intended lol). If you want to see more you can see these Second Life websites and blogs


  4. Hans Nagelschmidt

    May 12, 2021 at 10:15 am

    This was awesome! I would like you to clean up all this spam though


  5. Machelle Aaberg

    June 4, 2021 at 2:01 pm

    This was awesome! I would like you to clean up all this spam though


  6. Alysha Mclaen

    June 11, 2021 at 10:52 am

    This was great! I would like you to clean up all this spam though


Leave a Reply

Your email address will not be published. Required fields are marked *

Check Also

British Nutrition Foundation to launch Healthy Eating Week – New Food

The BNF is launching a new event to encourage people from all ages to improve their health…